A new class of Ru(II) polyazine agents with potential for photodynamic therapy.
نویسندگان
چکیده
Appending anthracene units to [(bpy)2Ru(dpp)](2+) results in Ru(II) agents that exhibit dynamic photoreactivity towards DNA and protein. [(Anthbpy)(bpy)Ru(dpp)](2+) and [(Anthbpy)2Ru(dpp)](2+) are the first metal-organic Ru(II) agent with dpp ligands shown to photomodify DNA in the presence or absence of oxygen, while also binding protein in an oxygen-dependent manner.
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ورودعنوان ژورنال:
- Chemical communications
دوره 52 13 شماره
صفحات -
تاریخ انتشار 2016